Lawson, a junior, suffered a sprained MCL in his left knee in the Tigers' Capital One Orange Bowl win over Oklahoma on Dec. 31, left the game early and didn't return.
"There's a very good chance I'll play," Lawson said. "I'm just trying to get my knee stronger before Monday."
Lawson, a Lombardi Award finalist who leads the nation in tackles for loss (23.5), will be key to the Tigers' defensive efforts against the Crimson Tide.
Asked to put a percentage on the chance that he plays, Lawson said "60 percent" but emphasized there's still time to improve before kickoff (8:30 p.m. ET, ESPN).
Lawson said he is getting treatment from Clemson's training staff twice a day for a total of about two hours daily. He practiced Thursday but noted that he has been limited.
"I'm getting better every day," Lawson said.
Shaq Lawson's preparing to play Monday
Clemson DE Shaq Lawson announces during media day that despite spraining his MCL in the Orange Bowl against Oklahoma, he feels like he's fully recovering and ready to play in the matchup against Alabama.