29-year-old Francisco Cintron, 42-year-old Raymond Giordano, and 26-year-old Israel Martinez were taken into custody Wednesday.
Authorities with the Horsham, Upper Moreland, Hatboro and Cheltenham police departments executed a search warrant at a home on Blair Mill Road.
Several bags of heroin and an undisclosed amount of money were found inside.
All three suspects remain in custody at the Montgomery County Correctional Facility in lieu of bail.