The accident happened before 2:30 p.m. Monday on I-76 West near the University Avenue exit.
There was no immediate word of any injuries.
Traffic was at a crawl on the expressway for nearly an hour.
Westbound traffic was being directed off the expressway at Exit 346B, the Vare Avenue exit, before crews were able to move the truck.
Traffic was moving again by 3:00 p.m.