Stephen Myers, 39, of the 200 block of Werden Drive in New Castle, was arrested on Monday.
According to investigators, officers were called to the Christiana Medical Center for the reported abuse of an elderly woman.
Police say they learned the victim was unable to care for herself and relied heavily on her son, identified as Myers.
Myers' mother had injuries to her upper body and evidence of being mistreated, police said.
Myers has been charged with intentional abuse, neglect, exploitation or mistreatment of an infirmed adult and assault in the second degree.
He was released on $8,000 unsecured bond and issued a no contact order.
