The fire broke out just after 7 p.m. Thursday in the 4800 block of Garden Street at John D' Orazio and Sons Incorporated.
Upon arrival, officials said heavy flames were showing through the roof of the building.
"We heard a loud explosion. The whole place was up within three minutes," said witness Robert Potts.
"We happen to look over, and it was this big a ball of orange coming from the building. ... The whole building was like pouring out with fire," said resident Carmen DeJesus.
A second alarm was struck in less than 10 minutes, and a third just after 8 p.m.
One witness, 14-year-old Kyle Diffield, captured the inferno as he was being evacuated from the Boys and Girls Club next door.
"The wall was burning and then the roof collapsed, and then you heard a big boom and it all went up in flames," said Diffield.
A firefighter was treated on the scene for minor injuries.
As of 11:30 p.m., the fire is reportedly under control.
Officials said they will be monitoring hot spots that may flare up throughout the night.