Investigators say that at about 2:30 a.m. the suspects broke into the house on the 3500 block of Dows Road.
Once inside, they overpowered the homeowner and tied him up.
They then combed through the house until they found some cash, then ran off.
They remain on the loose.
The homeowner was not seriously injured.
Police, so far, have not indicated if they know why the gunmen targeted the home.