Authorities in Armstrong County say the person was inside the home in the Pittsburgh suburb of Atwood when it exploded shortly before 4 p.m. Friday.
The Pittsburgh Post-Gazette reports that firefighters responded and the injured person was flown to the hospital. The victim's identity and condition are unknown.
Fire crews had the blaze under control shortly after 4:30 p.m.
The cause of the explosion is under investigation.
Information from: Pittsburgh Post-Gazette, http://www.post-gazette.com