Officials in Pulaski Township say the home has been a problem in the neighborhood for about a year. Neighbors called the township last week to complain when they saw rats coming out of the home.
Officials say the home's owner used to breed dogs there. The woman, who is bankrupt, moved out in August and her husband is in a nursing home.
The Beaver County Times reports that an exterminator hopes to kill about 95 percent of the rats before the home is demolished Friday. Officials will erect a perimeter around the home to try and prevent any rats that survive from going into neighboring homes.