It happened around 8:30 p.m. inside TJ's Lounge in the 800 block of East Woodlawn Street in the city's Germantown section.
Police say a 35-year-old man was shot multiple times. He was pronounced dead at the scene.
There have been no arrests.
The man killed has not been identified. There was no word on if he was an employee or customer.
Police say the shooting does not appear to be as a result of a robbery.