A 60-count indictment was handed down against Mayoshi Sanders and the members of the Sanders Drug Trafficking Organization.
Authorities say they sold crack cocaine and other drugs in the Courtyard Apartments-Riverview and in other areas of South Philadelphia.
According to the indictment, the Sanders DTO distributed in excess of 500 grams of cocaine and 280 grams of crack cocaine between March 2009 and August 30, 2011.
"Thanks to the successful partnership between the FBI and the Philadelphia Police Department, another significant drug trafficking organization in Philadelphia has been disrupted," U.S Attorney Zane Memeger said in a statement.
"Law abiding city residents should not have to live in fear of a domino effect from illegal activity that is happening across the street, down the block, or in their own development," said Philadelphia Police Commissioner Charles Ramsey in a statement.
The suspects are:
Mayoshi Sanders, 36, of Philadelphia
Tiyeak Cook, 34, of Philadelphia
Jamal Stewart , 27, of Philadelphia
Thomas Bowie, 19, of Philadelphia
Elizabeth Cadogen, 38, of Philadelphia
William Frisby, 33, of Philadelphia
Kwane Glover, 24, of Philadelphia
Harold Jackson , 46, of Philadelphia
Alfred Jenkins, 43, of Philadelphia
Philis McAllister, 25, of Philadelphia
Betty Ann McKinney, 48, of Philadelphia
Malani Sanders, 34, of Philadelphia
Davon Stokes, 22, of Philadelphia
Frank Wade, 20, of Philadelphia
Terrance Wade, 20, of Philadelphia
If convicted, each defendant faces a maximum possible sentence of life in prison.
The case was investigated by the Federal Bureau of Investigation's Safe Streets Violent Gang Task Force which includes members of Philadelphia Police Department's Narcotics Field Unit North and the Philadelphia Police Department's 3rd District.