Action News sports reporter Jeff Skversky learned Asomugha suffered a left knee injury.
However, an Eagles spokesman did not have any immediate details on the seriousness of the cornerback's injury.
This comes as fellow cornerback Dominique Rodgers-Cromartie is recovering from a high-ankle sprain.
The Eagles play the New England Patriots on Sunday.
A three-time Pro Bowl pick during his eight years with the Raiders, Asomugha signed a deal worth $60 million over five years with the Eagles during the off-season.