The accident happened around 10:10 p.m. at Street Road and St. Davids Avenue.
Arriving officers found the motorcyclist down on the highway after hitting a vehicle. He was transported to Abington Memorial Hospital where he later died.
The victim's identity has not yet been released.
According to investigators, the driver of the car turned into a group of five motorcyclists, striking the victim.
There is no word on charges at this time.