The fire started shortly before 10 a.m. at a twin home on the 1600 block of East 8th Street.
Chopper 6 over the scene showed flames and smoke billowing from the building.
The Red Cross says approximately three homes have been affected. They are assisting a total of four families, 10 people, with lodging, food, and clothing.
There is no word on injuries.
It is not clear what started the fire at this time.