The "Mandy" singer announced his cancer diagnosis in December.
"I'm going to change the narrative. It's not going to be a sad story, it needs to be a story of hope," she says.
Laughter is one of the best medicines for Angela Melchiorre, who uses comedy to educate people on the effects of chemotherapy.
Dole overcame severe World War II wounds to lead Senate GOP and run for president.
"Whether I like it or not, I think I'm a resilient survivor," Kathy Griffin said in an interview with ABC's "Nightline."
"While I certainly have some hurdles ahead, I also know that I join millions of Americans who face significant health challenges of their own."