The crash happened shortly after 10:00 a.m. at the intersection of Roosevelt Blvd. and Harbison Avenue.
According to fire officials, the fire truck was responding to a call on Vandike Street when the collision occurred.
One civilian received minor injuries and four firefighters were transported to Jeanes Hospital for observation as a result of the crash.
The accident remains under investigation.
The northbound lanes of the Boulevard remain closed at Harbison Avenue.
