Spokesman Jose Ubaldo says he has no immediate information on the extent of the injuries.
Footage from TV news helicopters shows the driver side of the vehicle crushed against the front of an Expo line train as firefighters used the Jaws of Life to pull the driver out of the car.
The cause of the crash is under investigation. There were no passengers on the train.
The Expo line connecting downtown to Culver City is set to open later this year.
