Authorities were called to a home on the 2800 block of Walnut Hill Street on Saturday afternoon.
Pennsylvania SPCA officials say the couple who lives there had their animals living in unsanitary conditions.
More than one dozen Maltese dogs and a few cats were pulled from the home.
"It's the worst I've ever seen in the basement. This is absolutely unbelievable. You cannot breathe in the basement," said George Bengal, Pennsylvania SPCA.
The SPCA says the dogs were kept in the basement where they lived in their own urine and feces.
Neighbors say they knew it was bad and some have even been complaining for almost two years.
"When they open that sliding door to the basement - ohh, the smell is really kicking," said one neighbor.
The couple may also face charges for breeding without a licensee after officials say they admitted to selling the puppies for $1,200 a piece.
