The St. Louis Rams couldn't keep up, especially after losing stars Steven Jackson and Sam Bradford on offense.
Vick rushed for 98 yards and passed for two scores, LeSean McCoy scored twice and DeSean Jackson topped 100 yards receiving as the Eagles began their self-proclaimed Super Bowl drive with a 31-13 victory over the St. Louis Rams on Sunday.
The Eagles had 239 yards rushing and were 8 for 11 on third downs. The defense applied constant pressure and piled up five sacks, two by Jason Babin.
Darryl Tapp forced a fumble by Bradford that led to an easy 56-yard touchdown return by Juqua Parker in the first quarter.
Jackson ran for a 47-yard score on the Rams' first play, untouched until a defender got a piece of his leg a step from the end zone. Soon after, he headed to the locker room, making just one more rush for 9 yards before calling it a day with a right leg injury. Bradford injured the right index finger on the followthrough to a pass in the fourth quarter, but did not break it.
Coach Steve Spanguolo said Bradford's injury could be nerve related.
One of the more boisterous crowds in recent memory at the Edward Jones Domes, flush with optimism off an unbeaten preseason, was muted by the Eagles' impressive display - combined with the injuries. In the second half, the Rams also lost their top cornerback, Ron Bartell, with a stinger, and their leading receiver from last year, Danny Amendola, with a dislocated left elbow.
Vick totaled 98 yards on eight carries and was 14 for 32 for 187 yards and two scores. McCoy had 122 yards on 15 carries and a 49-yard TD in the fourth quarter that finished it off, plus a 7-yard scoring reception in the first quarter.
Bradford was 17 for 30 for 188 yards. Jackson's backup, Cadillac Williams, had 91 yards on 19 carries.