The shootings happened just after midnight at the intersection of 10th and Tabor Road.
Officials say an augment between two men in a house in the 900 block of Wagner Avenue spilled out onto the street.
An 18-year-old male was shot multiple times in the torso and chest and pronounced dead at Einstein Hospital.
The other male, a 21-year-old was shot in the shoulder and listed in stable condition.
Police believe both fired on each other.
Police are hoping to gather more information from nearby surveillance cameras.