The new guidance was approved by the school board Thursday night and goes into effect Friday.
Masks will also be optional while riding the bus, and for school activities.
"Per Board approval on June 3, 2021, face masks will be optional for students and staff in school beginning, Friday, June 4, 2021, at 6 AM. This includes bus riding and school activities," a message reads on the district's website.
Neighboring school district, Central Bucks, also approved optional mask wearing for the final week of school.
Meanwhile, students at the School District of Philadelphia will still need to wear masks in the fall.