Organizers say Short will accept the Courage Award on behalf of his wife, who lost her three-year battle with cancer last year, at the annual Unforgettable Evening fundraising event next week.
Annette Bening is also being honored at the private star-studded dinner, where Conan O'Brien is serving as host and Rihanna is set to perform.
The Women's Cancer Research Fund is a program of the Entertainment Industry Foundation that supports research and education toward early diagnosis and innovative cures for women's cancers.
Tom Hanks, Rita Wilson, Steven Spielberg and Kate Capshaw serve as honorary chairs for the organization.
