Binh Thai Luc entered his plea Thursday to five counts of murder, plus special circumstances of committing multiple murders, robbery, burglary and lying in wait.
The 35-year-old appeared nervous and shook his head several times during the 20-minute hearing in San Francisco Superior Court. A judge set his bail at $25 million.
Prosecutors say Luc used a blunt instrument to kill 32-year-old Yuan Ji "Vincent" Lei, Lei's parents and Lei's girlfriend on March 23. The bodies were found by a relative at the family's home in the city's Ingleside District.
Authorities have not discussed a possible motive, but say they believe the victims were targeted.