It happened Thursday at the Fenwick Park Apartments in Elsmere.
Delaware State Police raided three apartments on Maple Avenue, one in the 1400 block and two others in the 1500 block.
Troopers seized more than 185 bags of heroin, drug paraphernalia, hundreds of rounds of ammunition, a machete, and two knives.
Charged with drug and other offenses are Branden Tucker, 21; Darin Matthews, 43; and Bernardo McKinney, 28, all of the Fenwick Park Apartments in Elsmere.
Authorities have issued an arrest warrant for William Johnson, 27, from the same apartment complex.
Anyone with information about Johnson's whereabouts is asked to contact the Delaware State Police Troop 2 Drug Unit at (302) 834-2630 extension 304, or Delaware Crime Stoppers at 1-800-TIP-3333.
Information may also be provided online via www.tipsubmit.com.