NBC said Tuesday that the new season of the show will also include Ashley Judd, Steve Buscemi, Vanessa Williams, Rosie O'Donnell and Kim Cattrall.
Kudrow, the former "Friends" star, is an executive producer for "Who Do You Think You Are?" and researched her own ancestry for the show last season. She said celebrities who take part are eager to find answers about their family history.
"Who Do You Think You Are?" returns early next year on NBC.