Shots rang out shortly before 9:00 a.m. in the vicinity of 15th and Catharine streets in the Graduate Hospital neighborhood.
The 36-year-old victim was found nearby at the corner of 18th and Fitzwater streets, having sustained a gunshot wound to the lower back.
He was transported to Hahnemann Hospital where he is listed in stable condition.
There is no word on what touched off the violence, but police say they are looking for multiple suspects.
The shooting happened just a block from the Universal Institute Charter School.
School officials said no students or staffers were injured and classes were not interrupted.