The body was discovered by a passerby at 7:28 a.m. in a lot in the 600 block of East 14th Street.
Authorities identified the victim as Janeal Jones.
Police say a preliminary investigation suggests that Jones was stabbed. Her death is being investigated as a homicide.
An autopsy is set to be conducted by the Chief Medical Examiner's Office to determine the cause of death.
Anyone with information is asked to call the Wilmington Police Confidential Tip Line at 302-576-3990 or Crime Stoppers at 1-800-TIP-3333.