It started around 1:40 a.m. Saturday when the red Toyota Camry struck a vehicle along the 3200 of North 16th Street, but fled the scene.
The operator of the vehicle that was hit confronted the driver of the Camry in the area of Broad and Ontario, which prompted the driver of the Camry to flee again - this time travelling westbound on Allegheny Avenue.
While fleeing at a high rate of speed, police say the Camry struck a parked vehicle along the 2600 block of Allegheny.
The impact of the crash trapped the driver and his passenger inside the Camry.
Firefighters worked to free both males who were then transported to Temple University Hospital.
The 29-year-old driver of the Camry suffered internal injuries and the 21-year-old passenger sustained a fractured pelvis, broken hand, and lacerated liver.
The incident remains under investigation and police say charges are pending.