Blake, who is a Black man, was shot multiple times at close range by police on Sunday while he tried to enter an SUV occupied by his 3, 5 and 8-year-old sons. Blake is now paralyzed and it would "take a miracle" for him to walk again, his lawyer announced on Tuesday.
"I'm sick and tired of having to protest and yet here I am and it's for the same reason," said Felicia Walker.
Stephany Reyes said, "I think it's upsetting that we're so used to that, that's what more upsetting than anything else."
During the march, Marcus Tuggles said despite this seeming routine at this point, he was still compelled to be there.
"I'm a father of a little girl, she's 9 going on 10, she has a fear of the police regarding me," he said.
Tuggles says he hopes one day the gap of what he believes is, gross misunderstanding of culture, can be bridged.
"We're missing humanity. You're judging based on the color of skin tone," he says
READ MORE: Jacob Blake needs 'a miracle' to walk again after police shot him, attorney says
Philadelphia's City Hall was fenced off and there was a heavy police presence throughout the city. The demonstration was peaceful with no issues reported by police.
Blake's shooting, which was caught on cellphone video, has sparked outrage and protests on the streets of Kenosha.
At least four major sports leagues postponed games Wednesday amid boycotts surrounding the shooting of Blake
The shooting follows months of demonstrations, riots and violence across the country in response to the death of George Floyd.
RELATED: 3 shot, 2 fatally, during Wisconsin protests