It happened at 10:15 a.m. Friday in the southbound lanes at Tyson Avenue.
Images from Chopper 6 HD showed a light-colored SUV lying on its roof in the middle of the intersection.
First responders were on the scene. Road crews were in the process of righting the SUV.
A dark-colored sedan with front-end damage was located a short distance away.
There was no immediate word on the number or extent of injuries.
Stay with Action News and 6abc.com for more information as it becomes available.