Guihua Zhang was last seen at her residence on the 6800 block of Torresdale Avenue on Tuesday, December 28, 2010.
Zhang is described as mentally deficient and suffers from Alzheimer's, she also requires daily medication.
She is 54-years old, 5'1, 100 pounds, with brown eyes and black hair. She was last seen wearing a black puffy coat and blue or black Nike sneakers.
Anyone with information is asked to contact Northeast Detective Division at 215-686-3153 or call 911.