27-year-old Rachael Markley was reported missing from her Sellersville home on Friday.
Police say she sent text messages indicating the possibility she may be in danger.
Markley is described as a white female, five feet tall, 140 pounds with blonde hair and green eyes.
Police believe she may be in Philadelphia or Central Montgomery County.
Anyone with information on Markley's whereabouts is urged to contact Perkasie Police at 215-257-6876.