Danny Granger had 18 points, Marquis Daniels finished with 17 points and 10 rebounds, and T.J. Ford added 12 points and seven assists for Indiana (4-4).
The 76ers tied it at 90 on Iguodala's free throw with 3:14 left in the fourth quarter and took their first lead, 92-90, on Miller's layup.
Young's two free throws capped a 9-0 run by the 76ers and gave them a 94-90 advantage with 1:31 left. Granger's jumper made it 94-92 and, following a missed shot by Brand, the Pacers had a chance to tie it or take the lead. However, Daniels missed a wide open 3-pointer with time winding down.
The Pacers jumped out to a 9-0 lead before Philadelphia got on the scoreboard on Samuel Dalembert's dunk nearly 4 minutes into the game. The 76ers started 0-of-7 from the field and finished the first quarter 5-of-21.
Indiana, which shot 59 percent and hit four of eight 3-point attempts, took a 38-13 lead on Jarrett Jack's layup to end the first period. The Pacers tied a season high for points in a quarter, while the 76ers tied a season low.
After falling behind by 26 points to begin the second quarter, Philadelphia slowly chipped away at the deficit, eventually getting to 57-49 on Brand's free throw late in the first half. Young had 12 points in the period.
Notes: Pacers G Mike Dunleavy (sore right knee) missed Friday's game and has yet to play this season. ... Granger started after missing Wednesday night's victory over New Jersey with a thigh cramp. ... Pacers rookie G Brandon Rush and 76ers G Kareem Rush both entered the game with 4:31 left in the first quarter. It was the first time the brothers have faced each other in the NBA. During the second quarter, a Pacers fan yelled to Kareem Rush, "Hey Kareem, can you get me your brother's autograph?" Kareem, sitting on the bench, looked back and smiled.
