Priyadi Kardono, a spokesman for the ministry's Disaster Management Agency, said Friday 715 people have been confirmed dead and 2,400 hospitalized.
Wednesday's 7.6 undersea earthquake caused devastation across large parts of West Sumatra. The most casualties were reported in the regional capital, Padang.
Kardono said more than 20,000 buildings and houses have been seriously damaged or destroyed, and nearly 3,000 people may still be trapped in Padang and six other districts.
Search and rescue teams were trying to find survivors, and a foreign aid effort flew in tents, water, medicine, food and hundreds of emergency workers.