Lawyers for Preston Plevretes of Marlboro, N.J., say the brain injury occurred when Plevretes returned to play a month after he had suffered a concussion in practice at La Salle University.
They say La Salle failed to properly handle his complaints of headaches. La Salle settled the suit without admitting any wrongdoing.
The 23-year-old Plevretes now has limited speech, can walk only short distances and has short-term memory loss.
Lawyer Shanin Specter says the settlement will cover his need for lifetime, round-the-clock care.
The injury stems from a hit the then-sophomore took in a Nov. 5, 2005, game at Duquesne University.