Villanova (12-1), which has won seven games in a row since a 28-24 loss to New Hampshire this season, advances to host William & Mary in the semifinals next weekend.
Villanova's defense was stout against the New Hampshire (10-3), holding them to 84 yards total on offense for the game. On the first play from scrimmage, Villanova defensive back John Dempsey returned a fumble 4 yards for a touchdown en route to the easy win.
Villanova, which collected six sacks, held New Hampshire without a first down until 6:31 left in third quarter.
Chris Whitney attempted only five passes, completing three for 44 yards and a touchdown run for Villanova.