In fact, researchers say a cup of joe might make things worse.
A recent study in the journal Behavioral Neuroscience finds caffeine doesn't counter the effects of alcohol.
Co-author Thomas Gould of Temple University says combining coffee and booze can "lead to poor decisions with disastrous outcomes."
He says caffeine and alcohol makes for an awake drunk, not someone who is sober.
The researchers studied mice, but say their conclusions apply to people, too.