Kolb, who replaced Donovan McNabb as the team's starting quarterback, will be followed by Michael Vick and rookie Mike Kafka.
"I think what you look from a quarterback to do is to execute the offense and to lead the offense and to make sure that he manages the game the proper way," coach Andy Reid said of his expectations for Kolb. "So that's how I approach it with him. I think that with any quarterback in the National Football League. If they think that they are going to complete every ball then that's a good thing."
A second-round pick in 2007, Kolb has started just two games in his first three seasons. But the organization felt so strongly that he can be the No. 1 quarterback that McNabb, a six-time Pro Bowl pick, was traded to Washington in April.
Kolb filled in nicely when McNabb missed two games last year and became the first player in NFL history to throw for 300 yards in his first two starts.
"Very confident," Kolb said when asked how he feels going into this start. "I think we've got all of our pieces back pretty much. Of course, some of the offensive line are still dinged up, but we've got a lot of guys back out there and like I've said, we've been sharp here the past couple of days. We want to see what it's like game speed and game atmosphere."
Several injured players won't play against the Jaguars, including defensive end Victor Abiamiri, guard Todd Herremans, center Jamaal (Jackson) running backs Mike Bell and J.J. Arrington, wide receiver Hank Baskett, offensive linemen Nick Cole and Fenuki Tupou, defensive tackle Antonio Dixon and cornerback Macho Harris.