For Michael Vick and the Philadelphia Eagles, more misery.
Brees threw two touchdown passes, extending his NFL record streak to 51 games, and Patrick Robinson returned an interception 99 yards for a score to lead the Saints to a 28-13 win over the reeling Eagles on Monday night.
New Orleans (3-5), which bounced back from a dismal 34-14 loss at Denver, also got a 22-yard touchdown run from Chris Ivory.
The Eagles (3-5) lost their fourth straight, which is sure to keep the heat on Vick and embattled coach Andy Reid. Vick threw a 77-yard touchdown pass to DeSean Jackson in the third quarter, but that was about the only highlight for the visiting team which saw Vick sacked seven times.
Not that they didn't have their chances. The Eagles had first-and-goal four times and managed only two field goals by Alex Henery. In fact, they were outscored in those situations, with Robinson going the other way for a touchdown just when it looked like Philadelphia was on the verge of scoring.
Rubbing salt in the wound, Philadelphia squandered a chance to get back in the game with a brilliant trick play on a kickoff return. Riley Cooper laid flat in the end zone, unseen by the Saints, then popped up to take a cross-field lateral from Brandon Boykin.
Cooper streaked down the sideline for an apparent touchdown. Only one problem - Boykin's lateral was actually a forward pass by about a yard, ruining the play with a penalty. Cooper stood with his hands on his hips, in disbelief, as the officials brought it back.
Philadelphia finished with 447 yards - the eighth straight team to put up more than 400 yards on the Saints. That was already the longest streak of 400-yard games given up by a defense since at least 1950, and maybe in the history of the NFL, putting New Orleans on pace to shatter the record for most yards allowed in a season.
But New Orleans came through where it mattered most, giving up a season low in points. Their previous best was a 31-24 victory over San Diego.
Philadelphia's last gasp was a fourth-down pass that Vick threw away in the back of the end zone with 7 seconds left, apparently more concerned about avoiding another pick than tacking on a meaningless TD.
Brees kept his record touchdown streak going, hooking up with Marques Colston on a 1-yard scoring pass and Jimmy Graham from 6 yards out.
The Saints quarterback finished 21 of 27 for 239 yards, a big improvement on his 22-of-42 showing against the Broncos. Brees also got plenty of help from the running game, which came into the league ranked last in the league.
Ivory, Pierre Thomas and Mark Ingram combined for 136 yards, each breaking off double-digit gains.
The embattled Saints defense kept the heat on Vick and the beating made it tough for No. 7 to establish any rhythm. He finished 22 of 41 for 272 yards and really couldn't be blamed for Robinson's interception, which went off the hands of tight end Brent Celek.
Celek had a tough night. He also lost a fumble deep at the New Orleans 8 with just over 3 minutes remaining, essentially ending any hope of a Philadelphia comeback.