Sinofsky's departure comes just weeks after the Redmond, Wash., software company launched Windows 8, which represented a major overhaul of its ubiquitous computer operating system.
Microsoft Corp. said Monday it has promoted company veteran Julie Larson-Green to lead all its Windows software and hardware engineering. Tami Reller will take over responsibility for the Windows business, while retaining her posts as chief financial officer and chief marketing officer.
The company didn't say why Sinofsky is leaving.