Court records show a judge finalized the actress' divorce from Death Cab for Cutie frontman Ben Gibbard on Wednesday in Los Angeles.
Gibbard and Deschanel, who stars in Fox's "New Girl," were married in September 2009. They had no children together.
The actress filed for divorce in December 2011 after separating two months earlier.
The judgment does not provide financial details of the breakup, although it states that the former couple's marriage cannot be repaired by counseling or mediation.
Deschanel was nominated last week for a Golden Globe for her work on "New Girl."