37-year-old Win Min Htut was taken into custody after fleeing the site of the murder, officials say.
Htut is charged with criminal homicide, burglary and criminal trespass in the murder of his wife 37-year-old Thida Myint.
At 3:45 p.m. Tuesday, the couple's 16-year-old daughter called 911 to report the shooting outside their home on the 300 block of Central Park Avenue.
Police found Myint in the street suffering from a gunshot wound.
The couple's teenage daughter told authorities that the man and woman had gotten into an argument, which continued outside the home. That's where Thida Myint was shot.
Lehigh County District Attorney Jim Martin says the couple's 10-year-old son and 3-year-old daughter also witnessed the shooting.
Police say Htut took the 3-year-old girl from scene, but police are not calling it an abduction, as it was originally reported.
Martin says Htut got a ride with a passing motorist. The vehicle was stopped at a 7-Eleven on Union Boulevard in Allentown and Htut was taken into custody.
The victim's attorney John Ashcraft tells Action News his client and her husband were in court Tuesday morning where a Lehigh judge extended a protection from abuse order for another 6 months. The suspect could not have contact with his wife or their children.
An autopsy of the victim is scheduled for Wednesday.