It happened near the Swedesford Road exit around 6:30 a.m.
Police say a box truck and pickup collided near Swedesford Road exit just before 6:00 a.m.
The impact of the crash caused the box truck to flip over.
One person was injured.
Police shut down Route 202 north at the Route 30 bypass while they cleared the wreckage.
All lanes have since been opened.