None of the injuries were considered to be life-threatening.
The crash happened around 11 a.m. in the westbound lanes of the highway at the Conshohocken Curve.
The view from Chopper 6 HD showed a pickup truck flipped onto its side in front of a tractor trailer.
A number of other damaged cars were scattered around the scene.
For nearly two hours, both westbound lanes and one eastbound lane were closed.
The crash scene was cleared by 1 p.m.
The cause of the crash remains under investigation.