Pennsylvania State Police were called shortly after 11:30 a.m. to I-95 near the exit for Business Route 1.
The crash involved at least three vehicles.
A number of ambulances and emergency crews could be seen from Sky 6 cameras.
Chopper 6 over the scene showed at least one person being taken from one vehicle to an ambulance on a stretcher.
There is no official word on the number of injured.
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