It happened just after 8:00 a.m. in the northbound lanes of the Blue Route between I-95 and MacDade Blvd.
It is a multi-vehicle crash involving a tractor trailer.
State Police are still trying to figure out the exact cause of the accident and just how many vehicles are involved.
There is one jack-knifed tractor trailer, an overturned car and at least two other cars that need to be towed from the scene.
So far there have been no reports of any injuries.