Jrue Holiday led the Sixers with 21 points. Andres Nocioni and Evan Turner each scored 18. The Sixers are slumping at the wrong time as they get set to play Miami in the playoffs.
They lost for the fifth time in the last six games. They finished 41-41 and failed to post their first winning record since 2004-05. The Sixers earned their 40th victory on April 1.
The Sixers play the Heat in Game 1 on Saturday.
The Pistons finished the season 30-52 and face an offseason of potential major changes, from the underachieving roster to the coaching staff.