Speaking at the shooting scene, Capt. James Clark of the Homicide Unit said it appears that two men were firing at each other in a "run and gun battle" and that the 45-year-old woman was caught in the crossfire.
The shooting happened around 2:30 p.m. in the 1500 block of South Corlies Street. That woman, and a 22-year-old man, were hit.
According to investigators, the woman was shot in the head. She was taken to the Hospital of the University of Pennsylvania where she later died.
The 22-year-old man was found wounded a few blocks away, in the 1400 block of Patton Street. He was taken to HUP with three gunshot wounds to the arm and one in his side. He was listed in critical, but stable, condition.
Police say the man who was shot is being 'uncooperative.'
"We do believe he was a participant in this shooting, and we believe there is another shooter out there and we're trying to find out who that is," said Capt. Clark.
There was no word on a suspect or motive in this shooting. However, investigators found a .45 caliber semi-automatic weapon in a trash can behind a row home in the 1500 block of 30th Street.
Capt. Clark also said that about 18 shots were fired.