It happened July 20 around 5:25 p.m. at a store on Jerome Drive in Cheswold.
Police say the men walked into Wal-Mart and took an undisclosed amount of money from three different cash registers.
An investigation revealed that the suspects used a register key to gain access to the registers.
Police say the suspects were able to leave the store undetected and got away in a newer model blue Ford Edge.
The first suspect is described as a black male, 30-40 years-old, with a heavy build. He was last seen wearing a navy button up shirt, navy pants, brown work boots and a green hat.
The second man is described as a black male, 40-50 years-old, with a thin build. He was last seen wearing tan shorts, a green t-shirt, and a tan baseball cap.
Anyone with information is asked to contact Delaware Crime Stoppers at 1-800-TIP-3333. Information may also be provided at www.tipsubmit.com.