The accident happened around 12:15 a.m. Monday on the 3000 block of Highland Avenue.
According to police, a car rear ended a Roto Rooter work van, spinning the car around to the front of the van.
Two people in the car and the driver of the van were injured in the collision.
The victims were transported to the hospital with multiple injuries and are all listed in stable. Police say they are looking into whether speed was a factor, and if the driver of the car was under the influence.