The incident happened around 9:30 p.m. at Reading and Frazier Avenues in the Devonshire section of the township.
Police say a 2001 Suzuki Sidekick SUV flipped over, killing the driver.
The front seat passenger was air lifted to AtlantiCare Regional Health Care, Atlantic City Division for treatment. One other passenger was transported to the hospital by ambulance.
A fourth occupant refused medical treatment.
The deceased driver is identified as 66-year-old John Perona of the Elwood section of Mullica Township.
Police say that preliminary findings lead them to believe that the vehicle may have been speeding while attempting to negotiate a sharp turn in the road.
The collision is still under investigation. Anyone with information is urged to contact the police department at 609-561-7600.